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Articles of Interest

IN MEMORIAM
Stephen Heywood, 37; he opened his life to other ALS patients
By David Abel, Globe Staff  |  November 28, 2006

Plan would create lines of human stem cells
Baltimore Sun, June 7. 2006

In this article, noted stem cell researcher and Packard investigator Dr. John Gearhart comments on the implications this new, privately funded embryonic stem cell research may have, particularly with respect to ALS and other neurodegenerative diseases.

BOOK REVIEW
Luckiest Man: The Life and Death of Lou Gehrig
Lou Gehrig: A Biography

New England Journal of Medicine, Volume 353:854-855 August 25, 2005 Number 8
By any reckoning, Lou Gehrig was the best first baseman in the history of baseball. Jonathan Eig, a writer for the Wall Street Journal, deftly tells the story about how the son of impoverished German immigrants became a national hero, how he flourished, and how his career ended in the great misfortune of amyotrophic lateral sclerosis (ALS), the disease that now bears his name.

NEUROSCIENCE:
The Dark Side of Glia
(excerpt)
Science, Vol 308, Issue 5723, 778-781, 6 May 2005
Long ignored, the nervous system's glial cells may turn out to be key players in disease and prime targets for therapy.

UW Scientists Find Protein To Fight Neurological Diseases
Wisconsin State Journal, January 5, 2005
UW-Madison researchers, lead by Packard Center researcher Jeff Johnson, have found a protein that may stop the progression of neurological diseases such as Huntington's, Parkinson's, Lou Gehrig's and Alzheimer's.

ALS Lost Nerve Power
ScienCentral News, December 21, 2004
Scientists may have found the cause of a rare, inherited form of Lou Gehrig's disease. As this article reports, this could offer insight into potential therapies for all forms of this debilitating disease.

“Mike Was In the Kitchen Chopping Carrots…”
Washingtonian Magazine, October 12, 2004
Packard Center board member Meg Roggensack wrote about her husband’s battle with Lou Gehrig’s disease for The Washingtonian. Also read the transcript of Meg's online chat about the article and her life with Mike.

Scientists Find New Way Stem Cells Repair Organs
Washington Post, October 8, 2004
Embryonic stem cells, valued by researchers for their ability to become any kind of tissue that a body might need, also produce druglike compounds that can help ailing organs repair themselves, scientists are reporting today.

Jay Brodie: Keeping a Commitment
The Baltimore Sun, October 27, 2003
A tribute to M.J. "Jay" Brodie, a member of the Packard Center Board of Governors.

Are Stem Cells in Your Future?
Excerpts from a lecture sponsored by The Friends of the Johns Hopkins University Libraries on May 28, 2003 featuring noted stem cell researcher John Gearhart. Dr. Gearhart is an investigator and advisor for the Robert Packard Center for ALS Research at Johns Hopkins.
Recommended Reading

Birthday Party for 'Luckiest Man,' Game's Durable Icon
The New York Times, June 15, 2003
Elizabeth Angell, ALS advocate and daughter of Board member Jean Angell, is quoted in this article about Lou Gehrig's 100th birthday.

With Metals in Mind
The Scientist, June 2, 2003

Copper could be a culprit in Lou Gehrig's disease. Center investigators Valerie Culotta and Philip Wong are among the scientists researching this possibility.

Mending Paralysis
Hopkins Medical News, Winter 2002
A vibrant woman stricken with ALS and a young neurology researcher both rest their hopes in the curative powers of stem cells.

In the Name of Lou Gehrig
Hopkins Medical News, Summer 2000
More than 60 years after the “Iron Horse” succumbed to ALS, researchers appear at last to be making headway toward defeating the devastating neurological condition that killed him.

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Recent news from the Robert Packard Center for ALS Research:
William H. Adams Foundation Pumps New Energy, Funds into Search for ALS Cure - May 6, 2008
Tell-Tale Protein Clumping in ALS is Less Complex Than Expected - April 10, 2008

ALS Mouse Study Highlights Astrocytes' Strong Potential as Therapy Target - February 7, 2008

Exciting New Human ALS Trial: Lithium and Riluzole - February 7, 2008
ALS Treatment: A Matter of Cleaning House? - December 19, 2007

New Study Brings What Goes Wrong in Inherited ALS into Focus - September 18, 2007

New ALS Protein Could Be a Keystone - August 9, 2007
Muscles More Than Passive Victims in ALS, Study Suggests - June 29, 2007
Saer and O’Neill Named Packard Center Board Co-Chairs - June 28, 2007

Self-Attack? Self-Repair? First Real Look at Gene Activity in ALS Models Sparks Thirst for Answers - May 3, 2007

Model of Accelerated Familial ALS Sheds Light on Disease Process - April 6, 2007
Early News From First Large Search for Sporadic ALS Genes - February 20, 2007
Human Stem Cell Transplants Mature Into Neurons and Make Contacts in Rat Spinal Cord - February 14, 2007

First Vaccine for Familial ALS Shows Potential in Model Mice - January 29, 2007

Our Five-Year Plan? Let Human Cells EXcellerate Therapy - January 18, 2007




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