October 3, 2006
PACKARD CENTER MAKES HEADWAY USING NOBEL PRIZE-WINNING TECHNIQUE
Andrew Fire and Craig Mello, the two scientists who won the Nobel prize in physiology or medicine today, are not Packard researchers.
But the reason they won the prize -- they revealed and explained a principle called RNA interference -- was snapped up by Packard researcher Zuoshang Xu as something that might, at the least, help us understand ALS biology.
Packard researcher Zuoshang Xu presents his findings at the 6th Annual ALS Research Symposium.
And at the most, RNA interference could lead to the best sort of therapy, one that specifically targets ALS gene-based flaws and leaves the rest of the body untouched. You can read more about Xu's approach in this article from ALS Alert: A Gene Disconnect
And you can read how Xu and his colleagues are fine-tuning the technique in this journal article: Designing siRNA
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