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ALS Alert Newsletter | May

Gene Searches Move Ahead

Finding Genes in Record Time

bryan traynor


NIH scientist Bryan Traynor has turned what’s undeniably the newest tool in the hunt for disease genes to the service of ALS research. Exome sequencing, as it’s called, focuses on exons—the stretches of DNA that code for proteins. Because exons make up the “business” part of the human genome, centering on them hastens the search for ALS genes.

Recently, Traynor found new mutant genes with possible ties to specific cell processes targeted in ALS. “Exome sequencing,” he says, “should let us find genes that underlie sporadic or familial ALS in record time.”

From the 10th ALS Scientific Symposium

10th ALS Scientific Symposium




A Tally of Packard-Based Research in 2010

ALS Genes and Models: Keys to the Cause

On a Therapeutic Path

Underlying Molecular Pathways

The Right Tools for the Job

Defining ALS

Gene Searches Move Ahead

ALSO In this Issue

mcgready
Partners In Collaboration
Our yearly award ceremony and outpouring of appreciation came with special gratitude for 10 years of unfailing help.
microscope
New ALS Human Cell Cultures Underway

A handful of this country's stem-cell pioneers are meeting to change the face of research with the first large-scale cultures of human cells with ALS.


Johns Hopkins School of Medicine

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