Sami Barmada, MD, PhD
Mechanisms of initiation and progression in ALS
Motor neurons control all of our movements from walking to breathing. These cells are selectively hit early in ALS, but why motor neurons are so susceptible remains mysterious. Our goals are to (1) determine what makes motor neurons vulnerable in ALS, and (2) define how ALS spreads from neuron to neuron. With this knowledge, we will develop targeted treatments that prevent the death of motor neurons in ALS and prevent the spread of disease once it has begun.
Note: Funding for this project was made possible by The Boye Foundation